Evaluation of expression and function of vascular endothelial growth factor receptor 2, platelet derived growth factor receptors-alpha and -beta, KIT, and RET in canine apocrine gl...

Por Urie, Bridget K, Russell, Duncan S, Kisseberth, William C, London, Cheryl A
Publicado em 2012

Identification of myeloid derived suppressor cells in the peripheral blood of tumor bearing dogs

Por Sherger, Matthew, Kisseberth, William, London, Cheryl, Olivo-Marston, Susan, Papenfuss, Tracey L
Publicado em 2012

Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

Por Fossey, Stacey L, Bear, Misty D, Kisseberth, William C, Pennell, Michael, London, Cheryl A
Publicado em 2011

Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma

Por Brown, Megan E., Bear, Misty D., Rosol, Thomas J., Premanandan, Chris, Kisseberth, William C., London, Cheryl A.
Publicado no BMC Vet Res (2015)

Evaluation of the adverse event profile and pharmacodynamics of toceranib phosphate administered to dogs with solid tumors at doses below the maximum tolerated dose

Por Bernabe, Luis Feo, Portela, Roberta, Nguyen, Sandra, Kisseberth, William C, Pennell, Michael, Yancey, Mark F, London, Cheryl A
Publicado em 2013

Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines

Por Couto, Jason I, Bear, Misty D, Lin, Jiayuh, Pennel, Michael, Kulp, Samuel K, Kisseberth, William C, London, Cheryl A
Publicado em 2012

Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines

Por Clemente-Vicario, Francisco, Alvarez, Carlos E., Rowell, Jennie L., Roy, Satavisha, London, Cheryl A., Kisseberth, William C., Lorch, Gwendolen
Publicado no PLoS One (2015)

Overexpression of miR-9 in mast cells is associated with invasive behavior and spontaneous metastasis

Por Fenger, Joelle M, Bear, Misty D, Volinia, Stefano, Lin, Tzu-Yin, Harrington, Bonnie K, London, Cheryl A, Kisseberth, William C
Publicado em 2014

Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

Por Murahari, Sridhar, Jalkanen, Aimee L., Kulp, Samuel K., Chen, Ching-Shih, Modiano, Jaime F., London, Cheryl A., Kisseberth, William C.
Publicado no BMC Cancer (2017)

Characterization of STAT3 activation and expression in canine and human osteosarcoma

Por Fossey, Stacey L, Liao, Albert T, McCleese, Jennifer K, Bear, Misty D, Lin, Jiayuh, Li, Pui-Kai, Kisseberth, William C, London, Cheryl A
Publicado em 2009

AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit

Por Lin, Tzu-Yin, Fenger, Joelle, Murahari, Sridhar, Bear, Misty D., Kulp, Samuel K., Wang, Dasheng, Chen, Ching-Shih, Kisseberth, William C., London, Cheryl A.
Publicado em 2010

Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines

Por Breit, Megan N, Kisseberth, William C, Bear, Misty D, Landesman, Yosef, Kashyap, Trinayan, McCauley, Dilara, Kauffman, Michael G, Shacham, Sharon, London, Cheryl A
Publicado em 2014

Non-immunosuppressive FTY720-derivative OSU-2S mediates reactive oxygen species mediated cytotoxicity in canine B-cell lymphoma

Por Mani, Rajeswaran, Yan, Ribai, Mo, Xiaokui, Chen, Ching-Shih, Phelps, Mitch A., Klisovic, Rebecca, Byrd, John C., Kisseberth, William C., London, Cheryl A., Muthusamy, Natarajan
Publicado no Vet Comp Oncol (2016)

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines

Por Fenger, Joelle M., Roberts, Ryan D., Iwenofu, O. Hans, Bear, Misty D., Zhang, Xiaoli, Couto, Jason I., Modiano, Jaime F., Kisseberth, William C., London, Cheryl A.
Publicado no BMC Cancer (2016)

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

Por Li Pui-Kai, Schwartz Eric B, Li Chenglong, Lin Jiayuh, Bear Misty D, Fossey Stacey L, Fuchs James R, Fenger Joelle, Kisseberth William C, London Cheryl A
Publicado em 2011-03-01

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

Por Fossey, Stacey L, Bear, Misty D, Lin, Jiayuh, Li, Chenglong, Schwartz, Eric B, Li, Pui-Kai, Fuchs, James R, Fenger, Joelle, Kisseberth, William C, London, Cheryl A
Publicado em 2011

Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs

Por Paoloni, Melissa C., Mazcko, Christina, Fox, Elizabeth, Fan, Timothy, Lana, Susan, Kisseberth, William, Vail, David M., Nuckolls, Kaylee, Osborne, Tanasa, Yalkowsy, Samuel, Gustafson, Daniel, Yu, Yunkai, Cao, Liang, Khanna, Chand
Publicado em 2010

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

Por Scott, Milcah C., Sarver, Aaron L., Gavin, Katherine J., Thayanithy, Venugopal, Getzy, David M., Newman, Robert A., Cutter, Gary R., Lindblad-Toh, Kerstin, Kisseberth, William C., Hunter, Lawrence E., Subramanian, Subbaya, Breen, Matthew, Modiano, Jaime F.
Publicado em 2011

Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study

Por London, Cheryl A., Bernabe, Luis Feo, Barnard, Sandra, Kisseberth, William C., Borgatti, Antonella, Henson, Mike, Wilson, Heather, Jensen, Kiersten, Ito, Daisuke, Modiano, Jaime F., Bear, Misty D., Pennell, Michael L., Saint-Martin, Jean-Richard, McCauley, Dilara, Kauffman, Michael, Shacham, Sharon
Publicado em 2014

DEVELOPMENT OF A BRAIN METASTATIC CANINE PROSTATE CANCER CELL LINE

Por Thudi, Nanda K., Shu, Sherry T., Martin, Chelsea K., Lanigan, Lisa G., Nadella, Murali V.P., Van Bokhoven, Adrie, Werbeck, Jillian L., Simmons, Jessica K., Murahari, Sridhar, Kisseberth, William C., Breen, Matthew, Williams, Christina, Chen, Ching-Shih, McCauley, Laurie K., Keller, Evan T., Rosol, Thomas J.
Publicado em 2011