Non-immunosuppressive FTY720-derivative OSU-2S mediates reactive oxygen species mediated cytotoxicity in canine B-cell lymphoma

Por Mani, Rajeswaran, Yan, Ribai, Mo, Xiaokui, Chen, Ching-Shih, Phelps, Mitch A., Klisovic, Rebecca, Byrd, John C., Kisseberth, William C., London, Cheryl A., Muthusamy, Natarajan
Publicado no Vet Comp Oncol (2016)

FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma

Por Liu, Qing, Alinari, Lapo, Chen, Ching-Shih, Yan, Fengting, Dalton, James T., Lapalombella, Rosa, Zhang, Xiaoli, Mani, Rajeswaran, Lin, Teresa, Byrd, John C., Baiocchi, Robert A., Muthusamy, Natarajan
Publicado em 2010

OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway

Por Bai, Li-Yuan, Ma, Yihui, Kulp, Samuel K., Wang, Shu-Huei, Chiu, Chang-Fang, Frissora, Frank, Mani, Rajeswaran, Mo, Xiaokui, Jarjoura, David, Byrd, John C., Chen, Ching-Shih, Muthusamy, Natarajan
Publicado em 2011

Dual Targeting of the Cyclin/Rb/E2F and Mitochondrial Pathways in Mantle Cell Lymphoma with the Translation Inhibitor Silvestrol

Por Alinari, Lapo, Prince, Courtney J., Edwards, Ryan B., Towns, William, Mani, Rajeswaran, Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Pan, Li, Kinghorn, A. Douglas, Grever, Michael R., Baiocchi, Robert A., Lucas, David M.
Publicado em 2012

FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death

Por Alinari, Lapo, Mahoney, Emilia, Patton, John, Zhang, Xiaoli, Huynh, Lenguyen, Earl, Christian T., Mani, Rajeswaran, Mao, Yicheng, Yu, Bo, Quinion, Carl, Towns, William H., Chen, Ching-Shih, Goldenberg, David M., Blum, Kristie A., Byrd, John C., Muthusamy, Natarajan, Prætorius-Ibba, Mette, Baiocchi, Robert A.
Publicado em 2011

Decitabine enhances anti-CD33 monoclonal antibody BI 836858–mediated natural killer ADCC against AML blasts

Por Vasu, Sumithira, He, Shun, Cheney, Carolyn, Gopalakrishnan, Bhavani, Mani, Rajeswaran, Lozanski, Gerard, Mo, Xiaokui, Groh, Veronica, Whitman, Susan P., Konopitzky, Renate, Kössl, Christian, Bucci, Donna, Lucas, David M., Yu, Jianhua, Caligiuri, Michael A., Blum, William, Adam, Paul J., Borges, Eric, Rueter, Bjoern, Heider, Karl-Heinz, Marcucci, Guido, Muthusamy, Natarajan
Publicado no Blood (2016)

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

Por Lapalombella, Rosa, Sun, Qingxiang, Williams, Katie, Tangeman, Larissa, Jha, Shruti, Zhong, Yiming, Goettl, Virginia, Mahoney, Emilia, Berglund, Caroline, Gupta, Sneha, Farmer, Alicia, Mani, Rajeswaran, Johnson, Amy J., Lucas, David, Mo, Xiaokui, Daelemans, Dirk, Sandanayaka, Vincent, Shechter, Sharon, McCauley, Dilara, Shacham, Sharon, Kauffman, Michael, Chook, Yuh Min, Byrd, John C.
Publicado em 2012

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B cell cytotoxicity in chronic lymphocytic leukemia

Por Mani, Rajeswaran, Mao, Yicheng, Frissora, Frank W., Chiang, Chi-Ling, Wang, Jiang, Zhao, Yuan, Wu, Yun, Yu, Bo, Yan, Ribai, Mo, Xiaokui, Yu, Lianbo, Flynn, Joseph, Jones, Jeffrey, Andritsos, Leslie, Baskar, Sivasubramanian, Rader, Christoph, Phelps, Mitch A, Chen, Ching-Shih, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Publicado no Leukemia (2014)

Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals

Por Lapalombella, Rosa, Yeh, Yuh-Ying, Wang, Liwen, Ramanunni, Asha, Rafiq, Sarwish, Jha, Shruti, Staubli, Justin, Lucas, David M., Mani, Rajeswaran, Herman, Sarah E. M., Johnson, Amy J., Lozanski, Arletta, Andritsos, Leslie, Jones, Jeffrey, Flynn, Joseph M., Lannutti, Brian, Thompson, Peter, Algate, Paul, Stromatt, Scott, Jarjoura, David, Mo, Xiaokui, Wang, Dasheng, Chen, Ching-Shih, Lozanski, Gerard, Heerema, Nyla A., Tridandapani, Susheela, Freitas, Michael A., Muthusamy, Natarajan, Byrd, John C.
Publicado em 2012