Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals

Tetraspanins are commonly believed to act only as “molecular facilitators”, with no direct role in signal transduction. We herein demonstrate that upon ligation, CD37, a tetraspanin molecule expressed on mature normal and transformed B-cells, becomes tyrosine phosphorylated, associates with proximal...

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Bibliografische gegevens
Hoofdauteurs: Lapalombella, Rosa, Yeh, Yuh-Ying, Wang, Liwen, Ramanunni, Asha, Rafiq, Sarwish, Jha, Shruti, Staubli, Justin, Lucas, David M., Mani, Rajeswaran, Herman, Sarah E. M., Johnson, Amy J., Lozanski, Arletta, Andritsos, Leslie, Jones, Jeffrey, Flynn, Joseph M., Lannutti, Brian, Thompson, Peter, Algate, Paul, Stromatt, Scott, Jarjoura, David, Mo, Xiaokui, Wang, Dasheng, Chen, Ching-Shih, Lozanski, Gerard, Heerema, Nyla A., Tridandapani, Susheela, Freitas, Michael A., Muthusamy, Natarajan, Byrd, John C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360882/
https://ncbi.nlm.nih.gov/pubmed/22624718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.040
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