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Non-immunosuppressive FTY720-derivative OSU-2S mediates reactive oxygen species mediated cytotoxicity in canine B-cell lymphoma
OSU-2S is a FTY720 (Fingolimod) derivative that lacks immunosuppressive properties but exhibits strong anti-tumor activity in several hematological and solid tumor models. We have recently shown OSU-2S to mediate potent cytotoxicity in human mantle cell lymphoma cell lines and primary cells. We repo...
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| Publicat a: | Vet Comp Oncol |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093090/ https://ncbi.nlm.nih.gov/pubmed/27136276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12221 |
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