A novel liposomal formulation of FTY720 (Fingolimod) for promising enhanced targeted delivery

We describe here the development and characterization of the physicochemical and pharmacokinetic properties of a novel liposomal formulation for FTY720 delivery, LP-FTY720. The mean diameter of LP-FTY720 was ~157 nm, and the FTY720 entrapment efficiency was ~85%. The liposomal formulation protected...

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Autori principali: Mao, Yicheng, Wang, Jiang, Zhao, Yuan, Wu, Yun, Kwak, Kwang Joo, Chen, Ching-Shih, Byrd, John C., Lee, Robert J., Phelps, Mitch A., Lee, L. James, Muthusamy, Natarajan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134520/
https://ncbi.nlm.nih.gov/pubmed/23969101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.08.001
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