Application of In Silico and HTS Approaches to Identify Nuclear Import Inhibitors for Venezuelan Equine Encephalitis Virus Capsid Protein: A Case Study

by Shechter, Sharon, Thomas, David R., Jans, David A.
Published in Front Chem (2020)

Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scav...

by Kocher, Olivier, Birrane, Gabriel, Yesilaltay, Ayce, Shechter, Sharon, Pal, Rinku, Daniels, Kathleen, Krieger, Monty
Published 2011

Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds

by Crochiere, Marsha, Kashyap, Trinayan, Kalid, Ori, Shechter, Sharon, Klebanov, Boris, Senapedis, William, Saint-Martin, Jean-Richard, Landesman, Yosef
Published in BMC Cancer (2015)

Akt promotes Endocardial-Mesenchyme Transition

by Meadows, Kafi N, Iyer, Seema, Stevens, Mark V, Wang, Duanning, Shechter, Sharon, Perruzzi, Carole, Camenisch, Todd D, Benjamin, Laura E
Published 2009

Endothelial Akt Signaling Is Rate-Limiting for Rapamycin Inhibition of Mouse Mammary Tumor Progression

by Phung, Thuy L., Eyiah-Mensah, Godfred, O’Donnell, Rebekah K., Bieniek, Radoslaw, Shechter, Sharon, Walsh, Kenneth, Kuperwasser, Charlotte, Benjamin, Laura E.
Published 2007

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

by Shechter, Sharon, Thomas, David R., Lundberg, Lindsay, Pinkham, Chelsea, Lin, Shih-Chao, Wagstaff, Kylie M., Debono, Aaron, Kehn-Hall, Kylene, Jans, David A.
Published in Sci Rep (2017)

Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

by Shechter, Sharon, Thomas, David R., Lundberg, Lindsay, Pinkham, Chelsea, Lin, Shih-Chao, Wagstaff, Kylie M., Debono, Aaron, Kehn-Hall, Kylene, Jans, David A.
Published in Sci Rep (2018)

Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity

by DeBono, Aaron, Thomas, David R., Lundberg, Lindsay, Pinkham, Chelsea, Cao, Ying, Graham, J. Dinny, Clarke, Christine L., Wagstaff, Kylie M., Shechter, Sharon, Kehn-Hall, Kylene, Jans, David A.
Published in Sci Rep (2019)

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription

by Gerald, Damien, Adini, Irit, Shechter, Sharon, Perruzzi, Carole, Varnau, Joseph, Hopkins, Benjamin, Kazerounian, Shiva, Kurschat, Peter, Blachon, Stephanie, Khedkar, Santosh, Bagchi, Mandrita, Sherris, David, Prendergast, George C., Klagsbrun, Michael, Stuhlmann, Heidi, Rigby, Alan C., Nagy, Janice A., Benjamin, Laura E.
Published 2013

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

by Lapalombella, Rosa, Sun, Qingxiang, Williams, Katie, Tangeman, Larissa, Jha, Shruti, Zhong, Yiming, Goettl, Virginia, Mahoney, Emilia, Berglund, Caroline, Gupta, Sneha, Farmer, Alicia, Mani, Rajeswaran, Johnson, Amy J., Lucas, David, Mo, Xiaokui, Daelemans, Dirk, Sandanayaka, Vincent, Shechter, Sharon, McCauley, Dilara, Shacham, Sharon, Kauffman, Michael, Chook, Yuh Min, Byrd, John C.
Published 2012

RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

by Kazerounian, Shiva, Gerald, Damien, Huang, Minzhou, Chin, Y. Rebecca, Udayakumar, Durga, Zheng, Ningning, O'Donnell, Rebekah K., Perruzzi, Carole, Mangiante, Lee, Pourat, Jacob, Phung, Thuy L., Bravo-Nuevo, Arturo, Shechter, Sharon, McNamara, Stephanie, DuHadaway, James B., Kocher, Olivier N., Brown, Lawrence F., Toker, Alex, Prendergast, George C., Benjamin, Laura E.
Published 2012