Transfer RNA Methytransferases and Their Corresponding Modifications in Budding Yeast and Humans: Activities, Predications, and Potential Roles in Human Health

Por Towns, William L., Begley, Thomas J.
Publicado em 2012

Mutation of Prkar1a Causes Osteoblast Neoplasia Driven by Dysregulation of Protein Kinase A

Por Pavel, Emilia, Nadella, Kiran, Towns, William H., Kirschner, Lawrence S.
Publicado em 2008

Transfection-Induced Defects in Dynein-Driven Transport: Evidence that ICs Mediate Cargo-Binding

Por Towns, William L., Tauhata, Sinji B.F., Vaughan, Patricia S., Vaughan, Kevin T.
Publicado em 2009

The gene-specific codon counting database: a genome-based catalog of one-, two-, three-, four- and five-codon combinations present in Saccharomyces cerevisiae genes

Por Tumu, Sudheer, Patil, Ashish, Towns, William, Dyavaiah, Madhu, Begley, Thomas J.
Publicado em 2012

Tissue-Specific Ablation of Prkar1a Causes Schwannomas by Suppressing Neurofibromatosis Protein Production

Por Jones, Georgette N, Tep, Chhavy, Towns, William H, Mihai, Georgeta, Tonks, Ian D, Kay, Graham F, Schmalbrock, Petra M, Stemmer-Rachamimov, Anat O, Yoon, Sung Ok, Kirschner, Lawrence S
Publicado em 2008

Dual Targeting of the Cyclin/Rb/E2F and Mitochondrial Pathways in Mantle Cell Lymphoma with the Translation Inhibitor Silvestrol

Por Alinari, Lapo, Prince, Courtney J., Edwards, Ryan B., Towns, William, Mani, Rajeswaran, Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Pan, Li, Kinghorn, A. Douglas, Grever, Michael R., Baiocchi, Robert A., Lucas, David M.
Publicado em 2012

Milatuzumab-Conjugated Liposomes as Targeted Dexamethasone Carriers for Therapeutic Delivery in CD74(+ )B-cell Malignancies

Por Mao, Yicheng, Triantafillou, Georgia, Hertlein, Erin, Towns, William, Stefanovski, Matthew, Mo, Xiaokui, Jarjoura, David, Phelps, Mitch, Marcucci, Guido, Lee, Ly James, Goldenberg, David M., Lee, Robert J., Byrd, John C., Muthusamy, Natarajan
Publicado em 2012

Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice

Por Rozewski, Darlene M., Herman, Sarah E. M., Towns, William H., Mahoney, Emilia, Stefanovski, Matthew R., Shin, Jungook D., Yang, Xiaoxia, Gao, Yue, Li, Xiaobai, Jarjoura, David, Byrd, John C., Johnson, Amy J., Phelps, Mitch A.
Publicado em 2012

The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease

Por Patton, John T., Lustberg, Mark E., Lozanski, Gerard, Garman, Sabrina L., Towns, William H., Drohan, Callie M., Lehman, Amy, Zhang, Xiaoli, Bolon, Brad, Pan, Li, Kinghorn, A. Douglas, Grever, Michael R., Lucas, David M., Baiocchi, Robert A.
Publicado no Oncotarget (2014)

17-DMAG targets the nuclear factor-κB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition

Por Hertlein, Erin, Wagner, Amy J., Jones, Jeffrey, Lin, Thomas S., Maddocks, Kami J., Towns, William H., Goettl, Virginia M., Zhang, Xiaoli, Jarjoura, David, Raymond, Chelsey A., West, Derek A., Croce, Carlo M., Byrd, John C., Johnson, Amy J.
Publicado em 2010

The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model

Por Beckwith, Kyle A., Frissora, Frank W., Stefanovski, Matthew R., Towns, William H., Cheney, Carolyn, Mo, Xiaokui, Deckert, Jutta, Croce, Carlo M., Flynn, Joseph M., Andritsos, Leslie A., Jones, Jeffrey A., Maddocks, Kami J., Lozanski, Gerard, Byrd, John C., Muthusamy, Natarajan
Publicado em 2014

FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death

Por Alinari, Lapo, Mahoney, Emilia, Patton, John, Zhang, Xiaoli, Huynh, Lenguyen, Earl, Christian T., Mani, Rajeswaran, Mao, Yicheng, Yu, Bo, Quinion, Carl, Towns, William H., Chen, Ching-Shih, Goldenberg, David M., Blum, Kristie A., Byrd, John C., Muthusamy, Natarajan, Prætorius-Ibba, Mette, Baiocchi, Robert A.
Publicado em 2011

Characterization of a New Chronic Lymphocytic Leukemia Cell Line for Mechanistic In Vitro and In Vivo Studies Relevant to Disease

Por Hertlein, Erin, Beckwith, Kyle A., Lozanski, Gerard, Chen, Timothy L., Towns, William H., Johnson, Amy J., Lehman, Amy, Ruppert, Amy S., Bolon, Brad, Andritsos, Leslie, Lozanski, Arletta, Rassenti, Laura, Zhao, Weiqiang, Jarvinen, Tiina M., Senter, Leigha, Croce, Carlo M., Symer, David E., de la Chapelle, Albert, Heerema, Nyla A., Byrd, John C.
Publicado em 2013

Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)

Por Woyach, Jennifer A., Bojnik, Engin, Ruppert, Amy S., Stefanovski, Matthew R., Goettl, Virginia M., Smucker, Kelly A., Smith, Lisa L., Dubovsky, Jason A., Towns, William H., MacMurray, Jessica, Harrington, Bonnie K., Davis, Melanie E., Gobessi, Stefania, Laurenti, Luca, Chang, Betty Y., Buggy, Joseph J., Efremov, Dimitar G., Byrd, John C., Johnson, Amy J.
Publicado em 2014

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

Por Dubovsky, Jason A., Flynn, Ryan, Du, Jing, Harrington, Bonnie K., Zhong, Yiming, Kaffenberger, Benjamin, Yang, Carrie, Towns, William H., Lehman, Amy, Johnson, Amy J., Muthusamy, Natarajan, Devine, Steven M., Jaglowski, Samantha, Serody, Jonathan S., Murphy, William J., Munn, David H., Luznik, Leo, Hill, Geoffrey R., Wong, Henry K., MacDonald, Kelli K.P., Maillard, Ivan, Koreth, John, Elias, Laurence, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Panoskaltsis-Mortari, Angela, Byrd, John C., Blazar, Bruce R.
Publicado no J Clin Invest (2014)