Antibody-based Therapeutics for the Treatment of Human B cell Malignancies

Tekijä Baskar, Sivasubramanian, Muthusamy, Natarajan
Julkaistu 2013

Autologous lymphoma vaccines induce human T cell responses against multiple, unique epitopes

Tekijä Baskar, Sivasubramanian, Kobrin, Carol B., Kwak, Larry W.
Julkaistu 2004

Targeting malignant B cells with an immunotoxin against ROR1

Tekijä Baskar, Sivasubramanian, Wiestner, Adrian, Wilson, Wyndham H., Pastan, Ira, Rader, Christoph
Julkaistu 2012

Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity

Tekijä Kwong, Ka Yin, Baskar, Sivasubramanian, Zhang, Hua, Mackall, Crystal L., Rader, Christoph
Julkaistu 2008

Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies

Tekijä Yang, Jiahui, Baskar, Sivasubramanian, Kwong, Ka Yin, Kennedy, Michael G., Wiestner, Adrian, Rader, Christoph
Julkaistu 2011

Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodie...

Tekijä Dave, Hema, Anver, Miriam R., Butcher, Donna O., Brown, Patrick, Khan, Javed, Wayne, Alan S., Baskar, Sivasubramanian, Rader, Christoph
Julkaistu 2012

A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display

Tekijä Baskar, Sivasubramanian, Suschak, Jessica M., Samija, Ivan, Srinivasan, Ramaprasad, Childs, Richard W., Pavletic, Steven Z., Bishop, Michael R., Rader, Christoph
Julkaistu 2009

The New Zealand Black Mouse as a Model for the Development and Progression of Chronic Lymphocytic Leukemia

Tekijä Salerno, Erica, Yuan, Yao, Scaglione, Brian J., Marti, Gerald, Jankovic, Alexander, Mazzella, Fermina, Laurindo, Maria Fernanda, Despres, Daryl, Baskar, Sivasubramanian, Rader, Christoph, Raveche, Elizabeth
Julkaistu 2010

Siglec-6 on chronic lymphocytic leukemia cells is a target for post-allogeneic hematopoietic stem cell transplantation antibodies

Tekijä Chang, Jing, Peng, Haiyong, Shaffer, Brian C., Baskar, Sivasubramanian, Wecken, Ina C., Cyr, Matthew G., Martinez, Gustavo J., Soden, Jo, Freeth, Jim, Wiestner, Adrian, Rader, Christoph
Julkaisussa Cancer Immunol Res (2018)

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era

Tekijä Robinson, Hannah R., Qi, Junpeng, Cook, Erika M., Nichols, Cydney, Dadashian, Eman L., Underbayev, Chingiz, Herman, Sarah E. M., Saba, Nakhle S., Keyvanfar, Keyvan, Sun, Clare, Ahn, Inhye E., Baskar, Sivasubramanian, Rader, Christoph, Wiestner, Adrian
Julkaisussa Blood (2018)

Autocrine signaling by Wnt-5a deregulates chemotaxis of leukemic cells and predicts clinical outcome in chronic lymphocytic leukemia

Tekijä Janovska, Pavlina, Poppova, Lucie, Plevova, Karla, Plesingerova, Hana, Behal, Martin, Kaucka, Marketa, Ovesna, Petra, Hlozkova, Michaela, Borsky, Marek, Stehlikova, Olga, Brychtova, Yvona, Doubek, Michael, Machalova, Michaela, Baskar, Sivasubramanian, Kozubik, Alois, Pospisilova, Sarka, Pavlova, Sarka, Bryja, Vitezslav
Julkaisussa Clin Cancer Res (2015)

ROR1 targeted delivery of OSU-2S, a non-immunosuppressive FTY720 derivative exerts potent cytotoxicity in mantle cell lymphoma in-vitro and in-vivo.

Tekijä Mani, Rajeswaran, Chiang, Chi-Ling, Frissora, Frank W., Yan, Ribai, Mo, Xiaokui, Baskar, Sivasubramanian, Rader, Christoph, Klisovic, Rebecca, Phelps, Mitch A, Chen, Ching-Shih, Lee, Robert J., Byrd, John C., Baiocchi, Robert, Lee, L. James, Muthusamy, Natarajan
Julkaisussa Exp Hematol (2015)

The B-cell tumor–associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor

Tekijä Hudecek, Michael, Schmitt, Thomas M., Baskar, Sivasubramanian, Lupo-Stanghellini, Maria Teresa, Nishida, Tetsuya, Yamamoto, Tori N., Bleakley, Marie, Turtle, Cameron J., Chang, Wen-Chung, Greisman, Harvey A., Wood, Brent, Maloney, David G., Jensen, Michael C., Rader, Christoph, Riddell, Stanley R.
Julkaistu 2010

ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model

Tekijä Chiang, Chi-Ling, Goswami, Swagata, Frissora, Frank W., Xie, Zhiliang, Yan, Pearlly S., Bundschuh, Ralf, Walker, Logan A., Huang, Xiaomeng, Mani, Rajeswaran, Mo, Xiaokui M., Baskar, Sivasubramanian, Rader, Christoph, Phelps, Mitch A., Marcucci, Guido, Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Julkaisussa Blood (2019)

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

Tekijä Bagnara, Davide, Kaufman, Matthew S., Calissano, Carlo, Marsilio, Sonia, Patten, Piers E. M., Simone, Rita, Chum, Philip, Yan, Xiao-Jie, Allen, Steven L., Kolitz, Jonathan E., Baskar, Sivasubramanian, Rader, Christoph, Mellstedt, Hakan, Rabbani, Hodjattallah, Lee, Annette, Gregersen, Peter K., Rai, Kanti R., Chiorazzi, Nicholas
Julkaistu 2011

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B cell cytotoxicity in chronic lymphocytic leukemia

Tekijä Mani, Rajeswaran, Mao, Yicheng, Frissora, Frank W., Chiang, Chi-Ling, Wang, Jiang, Zhao, Yuan, Wu, Yun, Yu, Bo, Yan, Ribai, Mo, Xiaokui, Yu, Lianbo, Flynn, Joseph, Jones, Jeffrey, Andritsos, Leslie, Baskar, Sivasubramanian, Rader, Christoph, Phelps, Mitch A, Chen, Ching-Shih, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Julkaisussa Leukemia (2014)