CARs and other T cell therapies for MM: the clinical experience

Bằng Danhof, Sophia, Hudecek, Michael, Smith, Eric L.
Xuất bản năm Best Pract Res Clin Haematol (2018)

Adoptive T-cell therapy for B-cell malignancies

Bằng Hudecek, Michael, Anderson, Larry D, Nishida, Tetsuya, Riddell, Stanley R
Được phát hành 2009

Engineered T cells For Anti-Cancer Therapy

Bằng Turtle, Cameron J., Hudecek, Michael, Jensen, Michael C., Riddell, Stanley R.
Được phát hành 2012

CAR T cells targeting α(v)β(3) integrin are effective against advanced cancer in preclinical models

Bằng Wallstabe, Lars, Mades, Andreas, Frenz, Silke, Einsele, Hermann, Rader, Christoph, Hudecek, Michael
Xuất bản năm Adv Cell Gene Ther (2018)

Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies

Bằng Zhou, Xiang, Rasche, Leo, Kortüm, K. Martin, Danhof, Sophia, Hudecek, Michael, Einsele, Hermann
Xuất bản năm Front Immunol (2020)

Chemically programmable and switchable CAR-T therapy

Bằng Qi, Junpeng, Tsuji, Kohei, Hymel, David, Burke, Terrence R., Hudecek, Michael, Rader, Christoph, Peng, Haiyong
Xuất bản năm Angew Chem Int Ed Engl (2020)

Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T

Bằng Nerreter, Thomas, Letschert, Sebastian, Götz, Ralph, Doose, Sören, Danhof, Sophia, Einsele, Hermann, Sauer, Markus, Hudecek, Michael
Xuất bản năm Nat Commun (2019)

CAR T-Cells in Multiple Myeloma: State of the Art and Future Directions

Bằng Rodríguez-Lobato, Luis Gerardo, Ganzetti, Maya, Fernández de Larrea, Carlos, Hudecek, Michael, Einsele, Hermann, Danhof, Sophia
Xuất bản năm Front Oncol (2020)

Development of Tumor-Reactive T Cells After Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplant for Chronic Lymphocytic Leukemia

Bằng Nishida, Tetsuya, Hudecek, Michael, Kostic, Ana, Bleakley, Marie, Warren, Edus H., Maloney, David, Storb, Rainer, Riddell, Stanley R.
Được phát hành 2009

Safety of targeting ROR1 for cancer immunotherapy with chimeric antigen receptor-modified T cells in a primate model

Bằng Berger, S Carolina, Sommermeyer, Daniel, Hudecek, Michael, Berger, Michael, Balakrishnan, Ashwini, Paskiewicz, Paulina, Kosasih, Paula, Rader, Christoph, Riddell, Stanley
Xuất bản năm J Immunother Cancer (2014)

Chimeric antigen receptor-modified T cells derived from defined CD8(+) and CD4(+) subsets confer superior antitumor reactivity in vivo

Bằng Sommermeyer, Daniel, Hudecek, Michael, Kosasih, Paula L., Gogishvili, Tea, Maloney, David G., Turtle, Cameron J., Riddell, Stanley R.
Xuất bản năm Leukemia (2015)

Expression of programmed death-1 on lymphocytes in myeloma patients is lowered during lenalidomide maintenance

Bằng Danhof, Sophia, Schreder, Martin, Knop, Stefan, Rasche, Leo, Strifler, Susanne, Löffler, Claudia, Gogishvili, Tea, Einsele, Hermann, Hudecek, Michael
Xuất bản năm Haematologica (2018)

Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform

Bằng Rydzek, Julian, Nerreter, Thomas, Peng, Haiyong, Jutz, Sabrina, Leitner, Judith, Steinberger, Peter, Einsele, Hermann, Rader, Christoph, Hudecek, Michael
Xuất bản năm Mol Ther (2019)

Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T-cells

Bằng Hudecek, Michael, Lupo-Stanghellini, Maria-Teresa, Kosasih, Paula L., Sommermeyer, Daniel, Jensen, Michael C., Rader, Christoph, Riddell, Stanley R.
Được phát hành 2013

The non-signaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity

Bằng Hudecek, Michael, Sommermeyer, Daniel, Kosasih, Paula L., Silva-Benedict, Anne, Liu, Lingfeng, Rader, Christoph, Jensen, Michael C., Riddell, Stanley R.
Xuất bản năm Cancer Immunol Res (2014)

The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR-T cells

Bằng Mestermann, Katrin, Giavridis, Theodoros, Weber, Justus, Rydzek, Julian, Frenz, Silke, Nerreter, Thomas, Mades, Andreas, Sadelain, Michel, Einsele, Hermann, Hudecek, Michael
Xuất bản năm Sci Transl Med (2019)

Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

Bằng Berger, Carolina, Sommermeyer, Daniel, Hudecek, Michael, Berger, Michael, Balakrishnan, Ashwini, Paszkiewicz, Paulina J., Kosasih, Paula L., Rader, Christoph, Riddell, Stanley R.
Xuất bản năm Cancer Immunol Res (2014)

Inhibition of TGF-β-receptor signaling augments the antitumor function of ROR1-specific CAR T-cells against triple-negative breast cancer

Bằng Stüber, Tanja, Monjezi, Razieh, Wallstabe, Lars, Kühnemundt, Johanna, Nietzer, Sarah Louise, Dandekar, Gudrun, Wöckel, Achim, Einsele, Hermann, Wischhusen, Jörg, Hudecek, Michael
Xuất bản năm J Immunother Cancer (2020)

Adoptive Therapy with Chimeric Antigen Receptor Modified T Cells of Defined Subset Composition

Bằng Riddell, Stanley R., Sommermeyer, Daniel, Berger, Carolina, Liu, Lingfeng (Steven), Balakrishnan, Ashwini, Salter, Alex, Hudecek, Michael, Maloney, David G., Turtle, Cameron J.
Được phát hành 2014

ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models

Bằng Wallstabe, Lars, Göttlich, Claudia, Nelke, Lena C., Kühnemundt, Johanna, Schwarz, Thomas, Nerreter, Thomas, Einsele, Hermann, Walles, Heike, Dandekar, Gudrun, Nietzer, Sarah L., Hudecek, Michael
Xuất bản năm JCI Insight (2019)