Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform

Chimeric antigen receptor (CAR)-T cell immunotherapy is under intense preclinical and clinical investigation, and it involves a rapidly increasing portfolio of novel target antigens and CAR designs. We established a platform that enables rapid and high-throughput CAR-screening campaigns with reporte...

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Vydáno v:Mol Ther
Hlavní autoři: Rydzek, Julian, Nerreter, Thomas, Peng, Haiyong, Jutz, Sabrina, Leitner, Judith, Steinberger, Peter, Einsele, Hermann, Rader, Christoph, Hudecek, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369451/
https://ncbi.nlm.nih.gov/pubmed/30573301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.015
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