A cellular platform for the evaluation of immune checkpoint molecules

Blockade of the T cell coinhibitory molecules CTLA-4 and PD-1 has clinical utility to strengthen T cell responses. In addition to these immune checkpoints an ever-growing number of molecules has been implicated in generating coinhibitory signals in T cells. However, investigating coinhibitory molecu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jutz, Sabrina, Hennig, Annika, Paster, Wolfgang, Asrak, Ömer, Dijanovic, Dejana, Kellner, Florian, Pickl, Winfried F., Huppa, Johannes B., Leitner, Judith, Steinberger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630299/
https://ncbi.nlm.nih.gov/pubmed/29029399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17615
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