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A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology

OBJECTIVE: Transgenic re‐expression enables unbiased investigation of T‐cell receptor (TCR)‐intrinsic characteristics detached from its original cellular context. Recent advancements in TCR repertoire sequencing and development of protocols for direct cloning of full TCRαβ constructs now facilitate...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Müller, Thomas R, Schuler, Corinna, Hammel, Monika, Köhler, Amelie, Jutz, Sabrina, Leitner, Judith, Schober, Kilian, Busch, Dirk H, Steinberger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681835/
https://ncbi.nlm.nih.gov/pubmed/33251011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1216
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