A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology

OBJECTIVE: Transgenic re‐expression enables unbiased investigation of T‐cell receptor (TCR)‐intrinsic characteristics detached from its original cellular context. Recent advancements in TCR repertoire sequencing and development of protocols for direct cloning of full TCRαβ constructs now facilitate...

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Bibliografische gegevens
Gepubliceerd in:Clin Transl Immunology
Hoofdauteurs: Müller, Thomas R, Schuler, Corinna, Hammel, Monika, Köhler, Amelie, Jutz, Sabrina, Leitner, Judith, Schober, Kilian, Busch, Dirk H, Steinberger, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681835/
https://ncbi.nlm.nih.gov/pubmed/33251011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1216
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