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Orthotopic T-Cell Receptor Replacement—An “Enabler” for TCR-Based Therapies

Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. However, the personalized nature of therapies using v...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Schober, Kilian, Müller, Thomas R., Busch, Dirk H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348731/
https://ncbi.nlm.nih.gov/pubmed/32492858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061367
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