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Orthotopic T-Cell Receptor Replacement—An “Enabler” for TCR-Based Therapies

Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. However, the personalized nature of therapies using v...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Schober, Kilian, Müller, Thomas R., Busch, Dirk H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348731/
https://ncbi.nlm.nih.gov/pubmed/32492858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061367
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