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Engineering Strategies to Enhance TCR-Based Adoptive T Cell Therapy

T cell receptor (TCR)-based adoptive T cell therapies (ACT) hold great promise for the treatment of cancer, as TCRs can cover a broad range of target antigens. Here we summarize basic, translational and clinical results that provide insight into the challenges and opportunities of TCR-based ACT. We...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Rath, Jan A., Arber, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349724/
https://ncbi.nlm.nih.gov/pubmed/32570906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061485
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