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Challenges of CAR- and TCR-T cell–based therapy for chronic infections

While therapy with T cells engineered with a chimeric antigen receptor (CAR) or a classical T cell receptor (TCR) is revolutionizing cancer treatment, its adoption in infectious diseases has been met with considerable resistance. Can we find its value for the cure of infections?

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Bertoletti, Antonio, Tan, Anthony Tanoto
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201928/
https://ncbi.nlm.nih.gov/pubmed/32163104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191663
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