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CAR T Cell Therapy: Challenges to Bench-to-Bedside Efficacy

Immunotherapy with T cells genetically modified to express chimeric antigen receptors (CARs) that target tumor-associated molecules have impressive efficacy in hematological malignancies. The field has now embraced the challenge of applying this approach to treat common epithelial malignancies, whic...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Srivastava, Shivani, Riddell, Stanley R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957501/
https://ncbi.nlm.nih.gov/pubmed/29311388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701155
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