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Needle in a Haystack: The Naïve Repertoire as a Source of T Cell Receptors for Adoptive Therapy with Engineered T Cells

T cell engineering with antigen-specific T cell receptors (TCRs) has allowed the generation of increasingly specific, reliable, and versatile T cell products with near-physiological features. However, a broad applicability of TCR-based therapies in cancer is still limited by the restricted number of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: D’Ippolito, Elvira, Wagner, Karolin I., Busch, Dirk H
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664211/
https://ncbi.nlm.nih.gov/pubmed/33171940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218324
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