A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology

OBJECTIVE: Transgenic re‐expression enables unbiased investigation of T‐cell receptor (TCR)‐intrinsic characteristics detached from its original cellular context. Recent advancements in TCR repertoire sequencing and development of protocols for direct cloning of full TCRαβ constructs now facilitate...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Müller, Thomas R, Schuler, Corinna, Hammel, Monika, Köhler, Amelie, Jutz, Sabrina, Leitner, Judith, Schober, Kilian, Busch, Dirk H, Steinberger, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681835/
https://ncbi.nlm.nih.gov/pubmed/33251011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1216
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