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Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies

In the last few years, monoclonal antibodies (mAbs) such as elotuzumab and daratutumab have brought the treatment of multiple myeloma (MM) into the new era of immunotherapy. More recently, chimeric antigen receptor (CAR) modified T cell, a novel cellular immunotherapy, has been developed for treatme...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Zhou, Xiang, Rasche, Leo, Kortüm, K. Martin, Danhof, Sophia, Hudecek, Michael, Einsele, Hermann
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793717/
https://ncbi.nlm.nih.gov/pubmed/33424871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.620312
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