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The New Zealand Black Mouse as a Model for the Development and Progression of Chronic Lymphocytic Leukemia
BACKGROUND: Similar to a subset of human patients who progress from monoclonal B lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL), New Zealand Black (NZB) mice have an age-associated progression to CLL. The murine disease is linked to a genetic abnormality in microRNA mir-15a/16-1 locus, re...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963456/ https://ncbi.nlm.nih.gov/pubmed/20839343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.20544 |
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