The New Zealand Black Mouse as a Model for the Development and Progression of Chronic Lymphocytic Leukemia

BACKGROUND: Similar to a subset of human patients who progress from monoclonal B lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL), New Zealand Black (NZB) mice have an age-associated progression to CLL. The murine disease is linked to a genetic abnormality in microRNA mir-15a/16-1 locus, re...

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Main Authors: Salerno, Erica, Yuan, Yao, Scaglione, Brian J., Marti, Gerald, Jankovic, Alexander, Mazzella, Fermina, Laurindo, Maria Fernanda, Despres, Daryl, Baskar, Sivasubramanian, Rader, Christoph, Raveche, Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963456/
https://ncbi.nlm.nih.gov/pubmed/20839343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.20544
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