Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

BACKGROUND: Osteosarcoma (OS) is the most common primary bone tumor in both humans and dogs and is the second leading cause of cancer related deaths in children and young adults. Limb sparing surgery along with chemotherapy has been the mainstay of treatment for OS. Many patients are not cured with...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Murahari, Sridhar, Jalkanen, Aimee L., Kulp, Samuel K., Chen, Ching-Shih, Modiano, Jaime F., London, Cheryl A., Kisseberth, William C.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5251323/
https://ncbi.nlm.nih.gov/pubmed/28109246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3046-6
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