AR-42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibition

Histone deacetylases (HDACs) play critical roles in apoptosis and contribute to the proliferation of cancer cells. AR-42 is a novel Class I and II HDAC inhibitor that shows cytotoxicity against various human cancer cell lines. The present study aims to identify the target of AR-42 in hepatocellular...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Mingming, Pan, Yida, Dorfman, Robert G., Chen, Zhaogui, Liu, Fuchen, Zhou, Qian, Huang, Shan, Zhang, Jun, Yang, Dongqin, Liu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007137/
https://ncbi.nlm.nih.gov/pubmed/26993777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8077
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