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Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis
Class I histone deacetylases (HDACs) inhibit expression of tumor suppressor genes by removing acetyl groups from histone lysine residues, thereby increasing cancer cell survival and proliferation. We evaluated the expression of class I HDACs in cholangiocarcinoma (CCA). HDAC3 expression was specific...
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| 發表在: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725102/ https://ncbi.nlm.nih.gov/pubmed/29245911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19660 |
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