Seed-in-Soil: Pancreatic Cancer Influenced by Tumor Microenvironment

Por Lin, Huey-Jen, Lin, Jiayuh
Publicado no Cancers (Basel) (2017)

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

Por Song, Hui, Wang, Renxiao, Wang, Shaomeng, Lin, Jiayuh
Publicado em 2005

LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy

Por Zuo, Mingxin, Li, Chenglong, Lin, Jiayuh, Javle, Milind
Publicado no Oncotarget (2015)

Inhibition of STAT3 Signaling Blocks the Anti-apoptotic Activity of IL-6 in Human Liver Cancer Cells

Por Liu, Yan, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Publicado em 2010

The Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Induces Apoptosis in Medulloblastoma and Glioblastoma Cells

Por Ball, Sarah, Li, Chenglong, Li, Pui-Kai, Lin, Jiayuh
Publicado em 2011

Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy

Por Wu, Xiaojuan, Cao, Yang, Xiao, Hui, Li, Chenglong, Lin, Jiayuh
Publicado no Mol Cancer Ther (2016)

LLL12 Inhibits Endogenous and Exogenous Interleukin-6-induced STAT3 Phosphorylation in Human Pancreatic Cancer Cells

Por Liu, Aiguo, Liu, Yan, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Publicado no Anticancer Res (2011)

Persistent GP130/STAT3 Signaling Contributes to the Resistance of Doxorubicin, Cisplatin, and MEK Inhibitor in Human Rhabdomyosarcoma Cells

Por Wu, Xiaojuan, Xiao, Hui, Wang, Ruoning, Liu, Lingling, Li, Chenglong, Lin, Jiayuh
Publicado no Curr Cancer Drug Targets (2016)

Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PAN...

Por Hutzen, Brian, Willis, William, Jones, Sarah, Cen, Ling, Deangelis, Stephanie, Fuh, Beng, Lin, Jiayuh
Publicado em 2009

Fragment-based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Tran...

Por Li, Huameng, Liu, Aiguo, Zhao, Zhenjiang, Xu, Yufang, Lin, Jiayuh, Jou, David, Li, Chenglong
Publicado no J Med Chem (2011)

Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells

Por Zhao, Chengguang, Xiao, Hui, Wu, Xiaojuan, Li, Chenglong, Liang, Guang, Yang, Shulin, Lin, Jiayuh
Publicado no Oncotarget (2015)

Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells

Por Chen, Xiang, Wei, Jia, Li, Chenglong, Pierson, Christopher R., Finlay, Jonathan L., Lin, Jiayuh
Publicado no Int J Oncol (2017)

Anti-Angiogenic Activity of a Small Molecule STAT3 Inhibitor LLL12

Por Bid, Hemant K., Oswald, Duane, Li, Chenglong, London, Cheryl A., Lin, Jiayuh, Houghton, Peter J.
Publicado em 2012

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer–Initiating Cells

Por Lin, Li, Liu, Aiguo, Peng, Zhengang, Lin, Huey-Jen, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Publicado no Cancer Res (2011)

Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells

Por Friedman, Lauren, Lin, Li, Ball, Sarah, Bekaii-Saab, Tanios, Fuchs, James, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Publicado em 2009

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

Por Lin, Li, Benson, Don M., DeAngelis, Stephanie, Bakan, Courtney E., Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Publicado em 2011

A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells

Por Xiao, Hui, Bid, Hemant Kumar, Jou, David, Wu, Xiaojuan, Yu, Wenying, Li, Chenglong, Houghton, Peter J., Lin, Jiayuh
Publicado no J Biol Chem (2015)

Reactivation of RASSF1A in Breast Cancer Cells by Curcumin

Por Du, Liping, Xie, Zhiliang, Wu, Lai-chu, Chiu, Ming, Lin, Jiayuh, Chan, Kenneth K., Liu, Shujun, Liu, Zhongfa
Publicado no Nutr Cancer (2012)

Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines

Por Couto, Jason I, Bear, Misty D, Lin, Jiayuh, Pennel, Michael, Kulp, Samuel K, Kisseberth, William C, London, Cheryl A
Publicado em 2012

ΔNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis

Por Bid, Hemant K., Roberts, Ryan D., Cam, Maren, Audino, Anthony, Kurmasheva, Raushan T., Lin, Jiayuh, Houghton, Peter J., Cam, Hakan
Publicado em 2013