STAT3 Is Necessary for Proliferation and Survival in Colon Cancer–Initiating Cells

STAT3 is constitutively activated in colon cancer but its contributions in cancer-initiating cells have not been explored. In this study, we characterized STAT3 in aldehyde dehydrogenase (ALDH)-positive (ALDH(+)) and CD133-positive (CD133(+)) subpopulations of human colon tumor cells that exhibited...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Lin, Li, Liu, Aiguo, Peng, Zhengang, Lin, Huey-Jen, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295768/
https://ncbi.nlm.nih.gov/pubmed/21900397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4660
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