Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells

BACKGROUND: STAT3 activation is frequently detected in breast cancer and this pathway has emerged as an attractive molecular target for cancer treatment. Recent experimental evidence suggests ALDH-positive (ALDH(+)), or cell surface molecule CD44-positive (CD44(+)) but CD24-negative (CD24(−)) breast...

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Hauptverfasser: Lin, Li, Hutzen, Brian, Lee, Hsiu-Fang, Peng, Zhengang, Wang, Wenlong, Zhao, Chongqiang, Lin, Huey-Jen, Sun, Duxin, Li, Pui-Kai, Li, Chenglong, Korkaya, Hasan, Wicha, Max S., Lin, Jiayuh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871589/
https://ncbi.nlm.nih.gov/pubmed/24376586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082821
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