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Anti-Angiogenic Activity of a Small Molecule STAT3 Inhibitor LLL12
BACKGROUND: Recent data indicate the Signal Transducer and Activator of Transcription 3 (STAT3) pathway is required for VEGF production and angiogenesis in various types of cancers. STAT3 inhibitors have been shown to reduce tumor microvessel density in tumors but a direct anti-angiogenic activity h...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328460/ https://ncbi.nlm.nih.gov/pubmed/22530037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035513 |
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