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A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin

Ovarian cancer is the fifth most common cause of cancer deaths among American women. Platinum and taxane combination chemotherapy represents the first-line approach for ovarian cancer, but treatment success is often limited by chemoresistance. Therefore, it is necessary to find new drugs to sensitiz...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Ruijie, Yang, Xiaozhi, Roque, Dana M., Li, Chenglong, Lin, Jiayuh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081214/
https://ncbi.nlm.nih.gov/pubmed/33909625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240145
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