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A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin

Ovarian cancer is the fifth most common cause of cancer deaths among American women. Platinum and taxane combination chemotherapy represents the first-line approach for ovarian cancer, but treatment success is often limited by chemoresistance. Therefore, it is necessary to find new drugs to sensitiz...

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Publicat a:PLoS One
Autors principals: Zhang, Ruijie, Yang, Xiaozhi, Roque, Dana M., Li, Chenglong, Lin, Jiayuh
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081214/
https://ncbi.nlm.nih.gov/pubmed/33909625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240145
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