A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells

Signal transducers and activators of transcription 3 (STAT3) signaling is persistently activated and could contribute to tumorigenesis of medulloblastoma. Numerous studies have demonstrated that inhibition of the persistent STAT3 signaling pathway results in decreased proliferation and increased apo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Xiao, Hui, Bid, Hemant Kumar, Jou, David, Wu, Xiaojuan, Yu, Wenying, Li, Chenglong, Houghton, Peter J., Lin, Jiayuh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2015
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319011/
https://ncbi.nlm.nih.gov/pubmed/25313399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616748
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