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Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin

BACKGROUND: Medulloblastoma is the most common type of pediatric brain tumor. Although numerous factors influence patient survival rates, more than 30% of all cases will ultimately be refractory to conventional therapies. Current standards of care are also associated with significant morbidities, gi...

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Detalhes bibliográficos
Main Authors: Hutzen, Brian, Bid, Hemant Kumar, Houghton, Peter J, Pierson, Christopher R, Powell, Kimerly, Bratasz, Anna, Raffel, Corey, Studebaker, Adam W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995427/
https://ncbi.nlm.nih.gov/pubmed/24646176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-206
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