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MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines

BACKGROUND: MicroRNAs (miRNAs) regulate the expression of networks of genes and their dysregulation is well documented in human malignancies; however, limited information exists regarding the impact of miRNAs on the development and progression of osteosarcoma (OS). Canine OS exhibits clinical and mo...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Fenger, Joelle M., Roberts, Ryan D., Iwenofu, O. Hans, Bear, Misty D., Zhang, Xiaoli, Couto, Jason I., Modiano, Jaime F., Kisseberth, William C., London, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057229/
https://ncbi.nlm.nih.gov/pubmed/27724924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2837-5
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