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ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

p63 is a structural homolog within the 53 family encoding two isoforms, ΔNp63 and TAp63. The oncogenic activity of ΔNp63 has been demonstrated in multiple cancers, however the underlying mechanisms that contribute to tumorigenesis are poorly characterized. Osteosarcoma (OSA) is the most common prima...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cam, Maren, Gardner, Heather L., Roberts, Ryan D., Fenger, Joelle M., Guttridge, Denis C., London, Cheryl A., Cam, Hakan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217036/
https://ncbi.nlm.nih.gov/pubmed/27391430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10406
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