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ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2
BACKGROUND: ΔNp63, a splice variant of p63, is overexpressed and exhibits oncogenic activity in many cancers including pancreatic and breast cancer and promotes cell survival by inhibiting apoptosis. Despite its role in tumorigenesis, mechanistic activity of ΔNp63 mediated oncogenic function in oste...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125704/ https://ncbi.nlm.nih.gov/pubmed/25085524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-559 |
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