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Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

BACKGROUND: We have previously demonstrated that both canine and human OSA cell lines, as well as 8 fresh canine OSA tumor samples, exhibit constitutive phosphorylation of STAT3, and that this correlates with enhanced expression of matrix metalloproteinase-2 (MMP2). While multiple signal transductio...

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Detalhes bibliográficos
Main Authors: Fossey, Stacey L, Bear, Misty D, Kisseberth, William C, Pennell, Michael, London, Cheryl A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079692/
https://ncbi.nlm.nih.gov/pubmed/21481226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-125
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