Overexpression of miR-9 in mast cells is associated with invasive behavior and spontaneous metastasis

Por Fenger, Joelle M, Bear, Misty D, Volinia, Stefano, Lin, Tzu-Yin, Harrington, Bonnie K, London, Cheryl A, Kisseberth, William C
Publicado em 2014

NF-κB p50 (nfkb1) contributes to pathogenesis in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia

Por Chen, Timothy L., Tran, Minh, Lakshmanan, Aparna, Harrington, Bonnie K., Gupta, Nikhil, Goettl, Virginia M., Lehman, Amy M., Trudeau, Stephen, Lucas, David M., Johnson, Amy J., Byrd, John C., Hertlein, Erin
Publicado no Blood (2017)

Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing

Por Dubovsky, Jason A., Chappell, Danielle L., Harrington, Bonnie K., Agrawal, Kitty, Andritsos, Leslie A., Flynn, Joseph M., Jones, Jeffrey A., Paulaitis, Michael E., Bolon, Brad, Johnson, Amy J., Byrd, John C., Muthusamy, Natarajan
Publicado em 2013

Anti-leukemic effects of all-trans retinoic acid in combination with Daratumumab in acute myeloid leukemia

Por Buteyn, Nathaniel J, Fatehchand, Kavin, Santhanam, Ramasamy, Fang, Huiqing, Dettorre, Gino M, Gautam, Shalini, Harrington, Bonnie K, Henderson, Sally E, Merchand-Reyes, Giovanna, Mo, Xiaokui, Benson, Don M, Carson, William E, Vasu, Sumithira, Byrd, John C, Butchar, Jonathan P, Tridandapani, Susheela
Publicado no Int Immunol (2018)

BRAF(V600E) accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia

Por Tsai, Yo-Ting, Lakshmanan, Aparna, Lehman, Amy, Harrington, Bonnie K., Lucas, Fabienne McClanahan, Tran, Minh, Sass, Ellen J., Long, Meixiao, Flechtner, Alan D., Jaynes, Florinda, La Perle, Krista, Coppola, Vincenzo, Lozanski, Gerard, Muthusamy, Natarajan, Byrd, John C., Grever, Michael R., Lucas, David M.
Publicado no Blood Adv (2017)

Selinexor suppresses Downstream Effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells

Por Zhong, Yiming, El-Gamal, Dalia, Dubovsky, Jason A., Beckwith, Kyle A., Harrington, Bonnie K., Williams, Katie E., Goettl, Virginia M., Jha, Shruti, Mo, Xiaokui, Jones, Jeffrey A., Flynn, Joseph M., Maddocks, Kami J., Andritsos, Leslie A., McCauley, Dilara, Shacham, Sharon, Kauffman, Michael, Byrd, John C., Lapalombella, Rosa
Publicado em 2014

Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma

Por Harrington, Bonnie K., Gardner, Heather L., Izumi, Raquel, Hamdy, Ahmed, Rothbaum, Wayne, Coombes, Kevin R., Covey, Todd, Kaptein, Allard, Gulrajani, Michael, Van Lith, Bart, Krejsa, Cecile, Coss, Christopher C., Russell, Duncan S., Zhang, Xiaoli, Urie, Bridget K., London, Cheryl A., Byrd, John C., Johnson, Amy J., Kisseberth, William C.
Publicado no PLoS One (2016)

The Bruton’s tyrosine kinase (BTK) inhibitor acalabrutinib demonstrates potent on-target effects and efficacy in two mouse models of chronic lymphocytic leukemia

Por Herman, Sarah E. M., Montraveta, Arnau, Niemann, Carsten U., Mora-Jensen, Helena, Gulrajani, Michael, Krantz, Fanny, Mantel, Rose, Smith, Lisa L., McClanahan, Fabienne, Harrington, Bonnie K., Colomer, Dolors, Covey, Todd, Byrd, John C., Izumi, Raquel, Kaptein, Allard, Ulrich, Roger, Johnson, Amy J., Lannutti, Brian J., Wiestner, Adrian, Woyach, Jennifer A.
Publicado no Clin Cancer Res (2016)

Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)

Por Woyach, Jennifer A., Bojnik, Engin, Ruppert, Amy S., Stefanovski, Matthew R., Goettl, Virginia M., Smucker, Kelly A., Smith, Lisa L., Dubovsky, Jason A., Towns, William H., MacMurray, Jessica, Harrington, Bonnie K., Davis, Melanie E., Gobessi, Stefania, Laurenti, Luca, Chang, Betty Y., Buggy, Joseph J., Efremov, Dimitar G., Byrd, John C., Johnson, Amy J.
Publicado em 2014

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

Por Dubovsky, Jason A., Flynn, Ryan, Du, Jing, Harrington, Bonnie K., Zhong, Yiming, Kaffenberger, Benjamin, Yang, Carrie, Towns, William H., Lehman, Amy, Johnson, Amy J., Muthusamy, Natarajan, Devine, Steven M., Jaglowski, Samantha, Serody, Jonathan S., Murphy, William J., Munn, David H., Luznik, Leo, Hill, Geoffrey R., Wong, Henry K., MacDonald, Kelli K.P., Maillard, Ivan, Koreth, John, Elias, Laurence, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Panoskaltsis-Mortari, Angela, Byrd, John C., Blazar, Bruce R.
Publicado no J Clin Invest (2014)