Epigenetic Modifiers: Basic Understanding and Clinical Development

per Piekarz, Richard L., Bates, Susan E.
Publicat a Clin Cancer Res (2009)

Entinostat: a promising treatment option for patients with advanced breast cancer

per Connolly, Roisin M, Rudek, Michelle A, Piekarz, Richard
Publicat a Future Oncol (2017)

Clinical Toxicities of Histone Deacetylase Inhibitors

per Subramanian, Srividya, Bates, Susan E., Wright, John J., Espinoza-Delgado, Igor, Piekarz, Richard L.
Publicat 2010

Cardiac Involvement with Lymphoma: A Review of the Literature

per O'Mahony, Deirdre, Piekarz, Richard L., Bandettini, W. Patricia, Arai, Andrew E., Wilson, Wyndham H., Bates, Susan E.
Publicat 2008

Romidepsin: A New Drug for the Treatment of Cutaneous T-Cell Lymphoma

per Frye, Robin, Myers, Mary, Axelrod, Karen C., Ness, Elizabeth A., Piekarz, Richard L, Bates, Susan E., Booher, Susan
Publicat a Clin J Oncol Nurs (2012)

Population pharmacokinetics and site of action exposures of veliparib with topotecan plus carboplatin in patients with haematological malignancies

per Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gobburu, Jogarao, Greer, Jacqueline M., Piekarz, Richard, Karp, Judith E., Pratz, Keith, Rudek, Michelle A.
Publicat a Br J Clin Pharmacol (2017)

A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat

per Peer, Cody J., Hall, Oliver M., Sissung, Tristan M., Piekarz, Richard, Balasubramaniam, Sanjeeve, Bates, Susan E., Figg, William D.
Publicat a Cancer Chemother Pharmacol (2018)

Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.

per Panicker, Jyoti, Li, Zhijie, McMahon, Christine, Sizer, Caroline, Steadman, Kenneth, Piekarz, Richard, Bates, Susan E., Thiele, Carol J.
Publicat a Cell Cycle (2010)

New Strategies in Peripheral T-cell lymphoma: Understanding Tumor Biology and Developing Novel Therapies

per Dunleavy, Kieron, Piekarz, Richard L., Zain, Jasmine, Janik, John E., Wilson, Wyndham H., O’Connor, Owen A., Bates, Susan E.
Publicat 2010

Exposure-Response of Veliparib to Inform Phase II Trial Design in Refractory or Relapsed Patients with Hematological Malignancies

per Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gobburu, Jogarao, Ji, Jiuping, Greer, Jacqueline M., Piekarz, Richard, Karp, Judith E., Pratz, Keith W., Rudek, Michelle A.
Publicat a Clin Cancer Res (2017)

Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors

per Grant, Cliona, Rahman, Fahd, Piekarz, Richard, Peer, Cody, Frye, Robin, Robey, Robert W, Gardner, Erin R, Figg, William D, Bates, Susan E
Publicat a Expert Rev Anticancer Ther (2010)

Reactivation of DNA viruses in association with histone deacetylase inhibitor therapy: a case series report

per Ritchie, David, Piekarz, Richard L., Blombery, Piers, Karai, Laszlo J., Pittaluga, Stefania, Jaffe, Elaine S., Raffeld, Mark, Janik, John E., Prince, H. Miles, Bates, Susan E.
Publicat 2009

A focus on the preclinical development and clinical status of the histone deacetylase inhibitor, romidepsin (depsipeptide, Istodax(®))

per Harrison, Simon J, Bishton, Mark, Bates, Susan E, Grant, Steven, Piekarz, Richard L, Johnstone, Ricky W, Dai, Yun, Lee, Becki, Araujo, Maria E, Prince, H Miles
Publicat a Epigenomics (2012)

Safety-modified episomal vectors for human gene therapy

per Cooper, Mark J., Lippa, Mara, Payne, Jennifer M., Hatzivassiliou, Georgia, Reifenberg, Erica, Fayazi, Behnaz, Perales, Jose C., Morrison, Laura J., Templeton, Dennis, Piekarz, Richard L., Tan, June
Publicat 1997

Population pharmacokinetics and exposure–response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias

per Singh, Renu, Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gojo, Ivana, Karp, Judith E., Greer, Jacqueline M., Chen, Alice, Piekarz, Richard, Kiesel, Brian F., Gobburu, Jogarao, Rudek, Michelle A., Beumer, Jan H.
Publicat a Cancer Chemother Pharmacol (2018)

Phase I Trial of Belinostat in Combination with 13-cis-Retinoic Acid in Advanced Solid Tumor Malignancies: A California Cancer Consortium NCI/CTEP Sponsored Trial.

per Luu, Thehang, Frankel, Paul, Beumer, Jan H, Lim, Dean, Cristea, Mihaela, Appleman, Leonard J, Lenz, Heinz J, Gandara, David R, Kiesel, Brian F, Piekarz, Richard L, Newman, Edward M
Publicat a Cancer Chemother Pharmacol (2019)

Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma

per Woo, Sukyung, Gardner, Erin R., Chen, Xiaohong, Ockers, Sandra B., Baum, Caitlin E., Sissung, Tristan M., Price, Douglas K., Frye, Robin, Piekarz, Richard L., Bates, Susan E., Figg, William D.
Publicat 2009

UGT1A1 Genotype-Dependent Dose Adjustment of Belinostat in Patients With Advanced Cancers Using Population Pharmacokinetic Modeling and Simulation

per Peer, Cody J., Goey, Andrew K. L., Sissung, Tristan M., Erlich, Sheryl, Lee, Min-Jung, Tomita, Yusuke, Trepel, Jane B., Piekarz, Richard, Balasubramaniam, Sanjeeve, Bates, Susan E., Figg, William D.
Publicat a J Clin Pharmacol (2015)

A Phase 2 Study of Alisertib (MLN8237) in Recurrent or Persistent Uterine Leiomyosarcoma: An NRG Oncology/Gynecologic Oncology Group Study 0231D

per Hyman, David M, Sill, Michael W, Lankes, Heather A, Piekarz, Richard, Shahin, Mark S, Ridgway, Mildred R, Backes, Floor, Tenney, Meaghen E, Mathews, Cara A., Hoffman, James S, Aghajanian, Carol, Hensley, Martee L
Publicat a Gynecol Oncol (2016)

Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for K(ATP) Channel

per Noonan, Anne M., Eisch, Robin A., Liewehr, David J., Sissung, Tristan M., Venzon, David J., Flagg, Thomas P., Haigney, Mark C., Steinberg, Seth M., Figg, William D., Piekarz, Richard L., Bates, Susan E.
Publicat a Clin Cancer Res (2013)