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Entinostat: a promising treatment option for patients with advanced breast cancer
Entinostat is a synthetic benzamide derivative histone deacetylase (HDAC) inhibitor, which potently and selectively inhibits class I and IV HDAC enzymes. This action promotes histone hyperacetylation and transcriptional activation of specific genes, with subsequent inhibition of cell proliferation,...
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| Vydáno v: | Future Oncol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Future Medicine Ltd
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5618943/ https://ncbi.nlm.nih.gov/pubmed/28326839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon-2016-0526 |
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