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Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.

As histone deacetylase inhibitors such as romidepsin (depsipeptide, FK228) complete successful Phase I clinical trials in pediatric solid tumors, it is important that their mechanisms of action are delineated in order to inform the development of subsequent clinical trials as single agents or in com...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Panicker, Jyoti, Li, Zhijie, McMahon, Christine, Sizer, Caroline, Steadman, Kenneth, Piekarz, Richard, Bates, Susan E., Thiele, Carol J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659113/
https://ncbi.nlm.nih.gov/pubmed/20404560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.9.11543
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