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Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.

As histone deacetylase inhibitors such as romidepsin (depsipeptide, FK228) complete successful Phase I clinical trials in pediatric solid tumors, it is important that their mechanisms of action are delineated in order to inform the development of subsequent clinical trials as single agents or in com...

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Vydáno v:Cell Cycle
Hlavní autoři: Panicker, Jyoti, Li, Zhijie, McMahon, Christine, Sizer, Caroline, Steadman, Kenneth, Piekarz, Richard, Bates, Susan E., Thiele, Carol J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659113/
https://ncbi.nlm.nih.gov/pubmed/20404560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.9.11543
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