The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

Pharmacologically-induced activation of replication competent proviruses from latency in the presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV-1 infection. However, until now, approaches to reverse HIV-1 latency in humans have yielded mixed results. Here, we r...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Søgaard, Ole S., Graversen, Mette E., Leth, Steffen, Olesen, Rikke, Brinkmann, Christel R., Nissen, Sara K., Kjaer, Anne Sofie, Schleimann, Mariane H., Denton, Paul W., Hey-Cunningham, William J., Koelsch, Kersten K., Pantaleo, Giuseppe, Krogsgaard, Kim, Sommerfelt, Maja, Fromentin, Remi, Chomont, Nicolas, Rasmussen, Thomas A., Østergaard, Lars, Tolstrup, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575032/
https://ncbi.nlm.nih.gov/pubmed/26379282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005142
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