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Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues
BACKGROUND: Topoisomerase I (Top1) is a proven target for cancer therapeutics. Recent data from the Fluorouracil, Oxaliplatin, CPT-11: Use and Sequencing (FOCUS) trial demonstrated that nuclear staining of Top1 correlates with chemotherapeutic efficacy. Such a correlation may help identify patients...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Public Library of Science
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532478/ https://ncbi.nlm.nih.gov/pubmed/23284638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050494 |
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