Validation of a Hypoxia-Inducible Factor-1α Specimen Collection Procedure and Quantitative ELISA in Solid Tumor Tissues

Hypoxia-inducible factor-1 alpha (HIF-1α) is an important marker of hypoxia in human tumors and has been implicated in tumor progression. Drugs targeting HIF-1α are being developed, but the ability to measure drug-induced changes in HIF-1α is limited by the lability of the protein in normoxia. Our g...

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Vydáno v:Anal Biochem
Hlavní autoři: Park, Sook Ryun, Kinders, Robert J., Khin, Sonny, Hollingshead, Melinda, Antony, Smitha, Parchment, Ralph E., Tomaszewski, Joseph E., Kummar, Shivaani, Doroshow, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810780/
https://ncbi.nlm.nih.gov/pubmed/24799347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.04.025
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