Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

Phosphorylated H2AX (γ-H2AX) is a sensitive marker for DNA double-strand breaks (DSBs), but the variability of H2AX expression in different cell and tissue types makes it difficult to interpret the meaning of the γ-H2AX level. Furthermore, the assays commonly used for γ-H2AX detection utilize labori...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Ji, Jiuping, Zhang, Yiping, Redon, Christophe E., Reinhold, William C., Chen, Alice P., Fogli, Laura K., Holbeck, Susan L., Parchment, Ralph E., Hollingshead, Melinda, Tomaszewski, Joseph E., Dudon, Quentin, Pommier, Yves, Doroshow, James H., Bonner, William M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291513/
https://ncbi.nlm.nih.gov/pubmed/28158293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171582
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