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The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

The maintenance of genome stability requires efficient DNA double-stranded break (DSB) repair mediated by the phosphorylation of multiple histone H2AX molecules near the break sites. The phosphorylated H2AX (γH2AX) molecules form foci covering many megabases of chromatin. the formation of γ-H2AX foc...

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Hlavní autoři: Nakamura, Asako J., Rao, V. Ashutosh, Pommier, Yves, Bonner, William M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086803/
https://ncbi.nlm.nih.gov/pubmed/20046100
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