Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

по Yankner, Bruce A., Lu, Tao
Опубликовано 2009

Inflammation links ageing to the brain

по Gabuzda, Dana, Yankner, Bruce A.
Опубликовано 2013

A γ-Secretase-independent Mechanism of Signal Transduction by the Amyloid Precursor Protein

по Hass, Matthew R., Yankner, Bruce A.
Опубликовано 2005

The Aging Stress Response

по Haigis, Marcia C., Yankner, Bruce A.
Опубликовано 2010

Neural mechanisms of ageing and cognitive decline

по Bishop, Nicholas A., Lu, Tao, Yankner, Bruce A.
Опубликовано 2010

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

по Song, Weihong, Nadeau, Philip, Yuan, Menglan, Yang, Xudong, Shen, Jie, Yankner, Bruce A.
Опубликовано 1999

β-Trcp couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation

по Liu, Chunming, Kato, Yoichi, Zhang, Zhuohua, Do, Viet Minh, Yankner, Bruce A., He, Xi
Опубликовано 1999

Acceleration of Amyloid β-Peptide Aggregation by Physiological Concentrations of Calcium

по Isaacs, Adrian M., Senn, David B., Yuan, Menglan, Shine, James P., Yankner, Bruce A.
Опубликовано 2006

Neuronal Localization of Presenilin-1 and Association with Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease

по Busciglio, Jorge, Hartmann, Henrike, Lorenzo, Alfredo, Wong, Caine, Baumann, Karlheinz, Sommer, Bernd, Staufenbiel, Matthias, Yankner, Bruce A.
Опубликовано в: J Neurosci (1997)

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system

по Lee, Peter C. W., Dodart, Jean-Cosme, Aron, Liviu, Finley, Lydia W., Bronson, Roderick T., Haigis, Marcia C., Yankner, Bruce A., Harper, J. Wade
Опубликовано 2013

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

по Sun, Fang, Park, Kevin K., Belin, Stephane, Wang, Dongqing, Lu, Tao, Chen, Gang, Zhang, Kang, Yeung, Cecil, Feng, Guoping, Yankner, Bruce A., He, Zhigang
Опубликовано 2011

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

по Kang, Chanhee, Xu, Qikai, Martin, Timothy D., Li, Mamie Z., Demaria, Marco, Aron, Liviu, Lu, Tao, Yankner, Bruce A., Campisi, Judith, Elledge, Stephen J.
Опубликовано в: Science (2015)

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

по Lipinski, Marta M., Zheng, Bin, Lu, Tao, Yan, Zhenyu, Py, Bénédicte F., Ng, Aylwin, Xavier, Ramnik J., Li, Cheng, Yankner, Bruce A., Scherzer, Clemens R., Yuan, Junying
Опубликовано 2010

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

по Loerch, Patrick M., Lu, Tao, Dakin, Kelly A., Vann, James M., Isaacs, Adrian, Geula, Chengiz, Wang, Jianbin, Pan, Ying, Gabuzda, Dana H., Li, Cheng, Prolla, Tomas A., Yankner, Bruce A.
Опубликовано 2008

REST and Stress Resistance in Aging and Alzheimer’s Disease

по Lu, Tao, Aron, Liviu, Zullo, Joseph, Pan, Ying, Kim, Haeyoung, Chen, Yiwen, Yang, Tun-Hsiang, Kim, Hyun-Min, Drake, Derek, Liu, X. Shirley, Bennett, David A., Colaiácovo, Monica P., Yankner, Bruce A.
Опубликовано 2014

Regulation of Lifespan by Neural Excitation and REST

по Zullo, Joseph M., Drake, Derek, Aron, Liviu, O’Hern, Patrick, Dhamne, Sameer C., Davidsohn, Noah, Mao, Chai-An, Klein, William H., Rotenberg, Alexander, Bennett, David A., Church, George M., Colaiácovo, Monica P., Yankner, Bruce A.
Опубликовано в: Nature (2019)

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

по Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C., Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Опубликовано в: Cell Rep (2019)

TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging

по Xu, Daichao, Jin, Taijie, Zhu, Hong, Chen, Hongbo, Ofengeim, Dimitry, Zou, Chengyu, Mifflin, Lauren, Pan, Lifeng, Amin, Palak, Li, Wanjin, Shan, Bing, Naito, Masanori Gomi, Meng, Huyan, Li, Ying, Pan, Heling, Aron, Liviu, Adiconis, Xian, Levin, Joshua Z., Yankner, Bruce A, Yuan, Junying
Опубликовано в: Cell (2018)

DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression

по Oberdoerffer, Philipp, Michan, Shaday, McVay, Michael, Mostoslavsky, Raul, Vann, James, Park, Sang-Kyu, Hartlerode, Andrea, Stegmuller, Judith, Hafner, Angela, Loerch, Patrick, Wright, Sarah M., Mills, Kevin D., Bonni, Azad, Yankner, Bruce A., Scully, Ralph, Prolla, Tomas A., Alt, Frederick W., Sinclair, David A.
Опубликовано 2008

Synaptic NMDA receptor activity boosts intrinsic antioxidant defences

по Papadia, Sofia, Soriano, Francesc X., Léveillé, Frédéric, Martel, Marc-Andre, Dakin, Kelly A., Hansen, Henrik H., Kaindl, Angela, Sifringer, Marco, Fowler, Jill, Stefovska, Vanya, Mckenzie, Grahame, Craigon, Marie, Corriveau, Roderick, Ghazal, Peter, Horsburgh, Karen, Yankner, Bruce A., Wyllie, David J. A., Ikonomidou, Chrysanthy, Hardingham, Giles E.
Опубликовано 2008