Evolution of the Aging Brain Transcriptome and Synaptic Regulation

Alzheimer's disease and other neurodegenerative disorders of aging are characterized by clinical and pathological features that are relatively specific to humans. To obtain greater insight into how brain aging has evolved, we compared age-related gene expression changes in the cortex of humans,...

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Hauptverfasser: Loerch, Patrick M., Lu, Tao, Dakin, Kelly A., Vann, James M., Isaacs, Adrian, Geula, Chengiz, Wang, Jianbin, Pan, Ying, Gabuzda, Dana H., Li, Cheng, Prolla, Tomas A., Yankner, Bruce A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553198/
https://ncbi.nlm.nih.gov/pubmed/18830410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003329
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