Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment

od Sigfridsson, Emma, Marangoni, Martina, Hardingham, Giles E., Horsburgh, Karen, Fowler, Jill H.
Izdano u J Neuroinflammation (2020)

Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice

od Searcy, James L., Le Bihan, Thierry, Salvadores, Natalia, McCulloch, James, Horsburgh, Karen
Izdano 2014

Endocytic Pathway Alterations in Human Hippocampus after Global Ischemia and the Influence of APOE Genotype

od McColl, Barry W., Graham, David I., Weir, Christopher J., White, Fiona, Horsburgh, Karen
Izdano 2003

Activation of Nrf2-Regulated Glutathione Pathway Genes by Ischemic Preconditioning

od Bell, Karen F. S., Fowler, Jill H., Al-Mubarak, Bashayer, Horsburgh, Karen, Hardingham, Giles E.
Izdano 2011

Angiotensin II-inhibition: effect on Alzheimer’s pathology in the aged triple transgenic mouse

od Ferrington, Linda, Palmer, Laura E., Love, Seth, Horsburgh, Karen J, Kelly, Paul AT, Kehoe, Patrick G
Izdano 2012

Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

od Sigfridsson, Emma, Marangoni, Martina, Johnson, Jeffrey A., Hardingham, Giles E., Fowler, Jill H., Horsburgh, Karen
Izdano u Sci Rep (2018)

4‐Hydroxynonenal Immunoreactivity is Increased in Human Hippocampus After Global Ischemia

od McCracken, Eileen, Graham, David I., Nilsen, Margaret, Stewart, Janice, Nicoll, James AR, Horsburgh, Karen
Izdano u Brain Pathol (2006)

Restoration of Oligodendrocyte Pools in a Mouse Model of Chronic Cerebral Hypoperfusion

od McQueen, Jamie, Reimer, Michell M., Holland, Philip R., Manso, Yasmina, McLaughlin, Mark, Fowler, Jill H., Horsburgh, Karen
Izdano 2014

Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease

od Ferrington, Linda, Miners, J Scott, Palmer, Laura E, Bond, Susan M, Povey, Joanne E, Kelly, Paul AT, Love, Seth, Horsburgh, Karen J, Kehoe, Patrick G
Izdano 2011

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

od Hase, Yoshiki, Craggs, Lucinda, Hase, Mai, Stevenson, William, Slade, Janet, Chen, Aiqing, Liang, Di, Ennaceur, Abdel, Oakley, Arthur, Ihara, Masafumi, Horsburgh, Karen, Kalaria, Raj N
Izdano u J Cereb Blood Flow Metab (2017)

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators

od Fowler, Jill H, McQueen, Jamie, Holland, Philip R, Manso, Yasmina, Marangoni, Martina, Scott, Fiona, Chisholm, Emma, Scannevin, Robert H, Hardingham, Giles E, Horsburgh, Karen
Izdano u J Cereb Blood Flow Metab (2017)

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

od James, Rachel, Searcy, James L, Le Bihan, Thierry, Martin, Sarah F, Gliddon, Catherine M, Povey, Joanne, Deighton, Ruth F, Kerr, Lorraine E, McCulloch, James, Horsburgh, Karen
Izdano 2012

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

od James, Rachel, Searcy, James L, Le Bihan, Thierry, Martin, Sarah F, Gliddon, Catherine M, Povey, Joanne, Deighton, Ruth F, Kerr, Lorraine E, McCulloch, James, Horsburgh, Karen
Izdano 2012

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory

od Kitamura, Akihiro, Saito, Satoshi, Maki, Takakuni, Oishi, Naoya, Ayaki, Takashi, Hattori, Yorito, Yamamoto, Yumi, Urushitani, Makoto, Kalaria, Raj N, Fukuyama, Hidenao, Horsburgh, Karen, Takahashi, Ryosuke, Ihara, Masafumi
Izdano u J Cereb Blood Flow Metab (2015)

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion

od Hase, Yoshiki, Craggs, Lucinda, Hase, Mai, Stevenson, William, Slade, Janet, Lopez, Dianne, Mehta, Rubin, Chen, Aiqing, Liang, Di, Oakley, Arthur, Ihara, Masafumi, Horsburgh, Karen, Kalaria, Raj N.
Izdano u J Neuroinflammation (2017)

Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

od Kitamura, Akihiro, Manso, Yasmina, Duncombe, Jessica, Searcy, James, Koudelka, Juraj, Binnie, Margaret, Webster, Scott, Lennen, Ross, Jansen, Maurits, Marshall, Ian, Ihara, Masafumi, Kalaria, Raj N., Horsburgh, Karen
Izdano u Sci Rep (2017)

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

od Bell, Karen F., Al-Mubarak, Bashayer, Fowler, Jill H., Baxter, Paul S., Gupta, Kunal, Tsujita, Tadayuki, Chowdhry, Sudhir, Patani, Rickie, Chandran, Siddharthan, Horsburgh, Karen, Hayes, John D., Hardingham, Giles E.
Izdano 2010

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

od Jones, Frances E, Murray, Lydia S, McNeilly, Sarah, Dean, Afshan, Aman, Alisha, Lu, Yinhui, Nikolova, Nija, Malomgré, Ruben, Horsburgh, Karen, Holmes, William M, Kadler, Karl E, Van Agtmael, Tom
Izdano u Hum Mol Genet (2019)

ApoE isoform-specific regulation of regeneration in the peripheral nervous system

od Comley, Laura H., Fuller, Heidi R., Wishart, Thomas M., Mutsaers, Chantal A., Thomson, Derek, Wright, Ann K., Ribchester, Richard R., Morris, Glenn E., Parson, Simon H., Horsburgh, Karen, Gillingwater, Thomas H.
Izdano 2011

Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

od Holland, Philip R, Searcy, James L, Salvadores, Natalia, Scullion, Gillian, Chen, Guiquan, Lawson, Greig, Scott, Fiona, Bastin, Mark E, Ihara, Masafumi, Kalaria, Rajesh, Wood, Emma R, Smith, Colin, Wardlaw, Joanna M, Horsburgh, Karen
Izdano u J Cereb Blood Flow Metab (2015)