Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

Apolipoprotein E (APOE)-ɛ4 is associated with a deleterious outcome after ischemic brain injury, which may involve abnormal regulation of mitochondrial function. We have assessed the mitochondrial proteomic response of APOE-ɛ3 and APOE-ɛ4 transgenic mice to transient global ischemic injury in the hi...

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Autors principals: James, Rachel, Searcy, James L, Le Bihan, Thierry, Martin, Sarah F, Gliddon, Catherine M, Povey, Joanne, Deighton, Ruth F, Kerr, Lorraine E, McCulloch, James, Horsburgh, Karen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323298/
https://ncbi.nlm.nih.gov/pubmed/21878944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.120
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