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Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice

The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ deposition was defined using quantitative label-free shotgun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Searcy, James L., Le Bihan, Thierry, Salvadores, Natalia, McCulloch, James, Horsburgh, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935958/
https://ncbi.nlm.nih.gov/pubmed/24587158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089970
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