Human Apolipoprotein E Redistributes Fibrillar Amyloid Deposition in Tg-SwDI Mice

Human apolipoprotein (ApoE) genotype influences the development of Alzheimer's disease and cerebral amyloid angiopathy (CAA). Specific mutations within the amyloid-β protein (Aβ) peptide have been identified that cause familial forms of CAA. However, the effect of APOE genotype on accumulation...

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Detalhes bibliográficos
Main Authors: Xu, Feng, Vitek, Michael P., Colton, Carol A., Previti, Mary Lou, Gharkholonarehe, Nastaran, Davis, Judianne, Van Nostrand, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657728/
https://ncbi.nlm.nih.gov/pubmed/18480287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1042-08.2008
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